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International Journal of Pharmaceutical and Clinical Research ; 14(7):631-638, 2022.
Article in English | EMBASE | ID: covidwho-1976190

ABSTRACT

Background: The pandemic, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) which poses unprecedented challenges to health-care systems around the world, another one is hypertension which is growing rapidly to epidemic levels in the developing countries, that’s why described by some clinicians as a ‘silent killer’. Objective: To study the prevalence of hypertension on disease progression and prognosis in patients with SARS-COV-2 positive adults and also assess the co relation between SARS-COV-2 positive adults with hypertension in tertiary care hospital. Methodology: A Hospital based, cross sectional, observational study was conducted among the 208 SARS-COV-2 positive adults in tertiary care hospital. A comparison between patients, admitted in Non-ICU and in ICU for treatment and management. Their demographic data, clinical manifestations, were collected and analyzed. Result: In our study 65 SARS-COV-2 positive subjects were found to be hypertensive with the prevalence of 31.3%. Where;new cases of hypertension were found to be with prevalence of 16 (24.6.%). Whereas, 69.4% of hypertensive subjects were on medication still having raised blood pressure (P < 0.05). However, failed to show that hypertension was an independent risk factor for COVID-19 mortality or severity (P > 0.05). Recommendation: It is necessary to create additional attention, awareness, change attitude so that they quit and avoid modifiable risk factors associated with hypertension and SARS-COV-2 infection and prevent worsening of their condition which leads to severe pneumonia, excessive inflammatory reactions, organ and tissue damage, and deterioration of the disease.

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